Right from its inception, the institute has executed many research schemes and programmes. The research activities are related mainly to two areas

·       Development of New Vaccines in the Biologicals production against common animals diseases and improvement in Vaccine production technology.

·       Diagnosis and study of animal diseases and their epidermiology for purposes of disease monitoring surveillance and forecasting.

Disease Investigation Sections:

This division consists of the Central Disease Investigation Laboratory located at Bangalore, there are 9    Regional Animal Disease Diagnostic Laboratory (ADD & IC) located at Belgaum, Bellary, Gulbarga, Davangere, Mysore, Mangalore, Shimoga, Bidar and wild animal disease diagnostic laboratory located at BNP, Bannerghatta, Bangalore. The ADD & IC have jurisdiction of 3-5 districts ADD & IC provide diagnostic service and cold storage facility for storing and supply of vaccines produced by the Institute. The ADD & IC are looked after by Regional Research Officers (RROs). ADD & IC also act as Information Centers for KVAFSU.

Research

        The following  are the ongoing research projects funded by different agencies at the Institute.

 

Project

Funding

1

Southern Regional Disease Diagnostic Laboratory (SRDDL)

GOI (100%)

2

All India Co-ordinated Research Project on Foot and Mouth Disease (AICRP on FMD)

ICAR GOK (75%) (25%)

3

Assistance to states for Control of Animal Diseases (ASCAD)

GOI GOK (75%) (25%)

4

National Project on Rinderpest Eradication (NPRE)

GOI (100%)

5

All India Co-ordinated Research Project on Animal Disease Monitoring and Surveillance (Collaborating Unit)

ICAR (100%)

6

All India Network Project on Blue Tongue Disease in Sheep

ICAR (100%)

7

DBT

  DBT (100%)

8

Leptospira

ICAR (100%)

        

    COMPLETED / ONGOING RESEARCH PROGRAMMES:

1.     Epidemiology of Foot and Mouse Disease (ICAR,1977)

2.     Use of synthetic dehydrated media in the production of vaccines.

3.   Tissue culture sheep pox-using lamb testis cells was carried out in Collaboration with the department of the veterinary Microbiology, University of Agricultural Sciences. The newly developed vaccine has given satisfactory protection under field conditions.

4.     The following studies on parthenium hysterophorus a weed associated with human allergy,were completed in collaboration with Indian Institute of Science.

·         Isolation, Identification and characterisation of parthenium, the toxic principle of parthenium plant.

·       Pathology of the toxic effects of parthenium in epidermental and natural situations -haematology ,gross and histopathology, clinical chemistry and immunological aspects.

·         The biochemical effects of the toxin in cell culture systemic using labelled compounds.

·         Detoxification and utilisation of parthenium as feed supplement to livestock and poultry.

·         The effect of parthenium, a sesquiterpene compound as an anticancerous agent.

5.  Behavour of Rinderpest virus of sheep origin.

                  ·    Transmission of RP virus isolated from sheep to cattle & vice- versa.

            ·    Change in the pattern of RP virus in affecting sheep & cattle.

6.      Prevalence of birth defects of animals as models to study human birth defects.

Wild life diseases:

1.     Rabies in elephants & leopard, HS & Anthrax in Bison and Elephants, RP in Bisons, Theileriasis & Babesiosis in Bisons, Trypanosomiasis in captiv & wildfelines. Studies on Epidemiology of Blue Tongue disease in sheep and molecular characteriztion of blue tongue virus (sponsored by Karnataka Sheep & Sheep products Development board).

2.      Development of DNA based diagonostics for diagnosis of leptospirosis.

3.       AICIRP on Animal Disease Monitoring and Surveillance (Regional Research Unit).

4.       Seroprevalence of trypanosomiasis in cattle and wild felines in karnataka.

5.       Production of Lasota vaccine.-1998 Test batch.

6.       Production of IBD vaccine.-1996-97 adapted to chicken embryos.

7.       Production of Tissue culture live sheep pox vaccine 2004.

8.       Production of Tissue culture Rabis vaccine using BHK cell line.

9.       Production of multiple emulsion HS vaccine.

10.   Production of HS & BQ combined alum precipitated vaccine -trial 1997.

11.   Freeze Dried ET toxioid -Trial Batch 1997.

12.   Studies on Avian Mycoplasmosis -Trial Batch June 2000.

13.   Bluetongue inactivated vaccine ( polyvalent ) - under trail.

TRAINING:

1.        The Institute is organising training programme in Animal Disease Diagnosis for Veterinarians from state Diagnostic Laboratories and also for Veterinarians from other state.

2.       The internship training programmes are conducted for BVSc, Students for Veterinary College, Bangalore and Bidar.

3.        Postgraduate students from other Universities are also given training in specified areas.

4.        Training facilities are provided at the Institute in Animal Health Coverage, disease diagnosis and biological  production.

·       To impart various aspects of animal health coverage to diary and poultry farmers, rural development agencies ,social workers, rural youth centers and members of voluntary organisations.

·        To Veterinary technical personnel of the state.

·        To Veterinary Officers of the state ,in charge of hospitals and Government livestock and poultry farms, various aspects of diagnosis, prevention  and control methods of animal diseases. Similar programmes are included for Veterinary, Management banking, Insurance & other professionals at state and national level.

·        The internship training programmes are conducted for BVSc, Students for Veterinary College, Bangalore and Bidar.  

·        Post graduate students from other Universities are also given training in specified areas.

FUTURE PLANS AND EXPANSION PROGRAMMES:

The future plans and expansion programmes of the institute are so envisaged as to include introduction of innovative technologies in the production of vaccines and diagnostics as well as to enhance the range of veterinary biologicals with a view to greatly reduce the economic losses to the farmer and make the state disease free zone if not total eradication. These programmes include:

1.  Usage of fermenter technology for large scale production of bacterial vaccines.

2.  Use of recombinant DNA technology for production of diagnostic antigens and kits.

3.  Development of new generation vaccines.

4.  Production of specific monoclonal antibodies for the development of diagnostic kits for speedy diagnosis.

5.  Development of facilities for training and initiating large-scale seriological / molecular epidemiological studies to combat animal diseases.

6.  Development of animal disease animal health extension education programmes for better control and prevention of animal diseases to enhance rural economy.

7.  Use of fermentation technology of cell culture based vaccines.

 

 

 

 

 

 
 
 

 

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